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Science and Research Center에서 연구 결과물과 책을 소개합니다. 언론 보도 자료도 함께 첨부 합니다.

COVID-19 Molecular Pathophysiology: Acetylation of Repurposing DrugsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces immune-mediated type 1 interferon (IFN-1) production, the pathophysiology of which involves sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) tetramerization and the cytosolic DNA sensor cyclic-GMP-AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling pathway. As a result, type I interferonopathies are exacerbated. Aspirin inhibits cGAS-mediated signaling through cGAS acetylation. Acetylation contributes to cGAS activity control and activates IFN-1 production and nuclear factor-κB (NF-κB) signaling via STING. Aspirin and dapsone inhibit the activation of both IFN-1 and NF-κB by targeting cGAS. We define these as anticatalytic mechanisms. It is necessary to alleviate the pathologic course and take the lag time of the odds of achieving viral clearance by day 7 to coordinate innate or adaptive immune cell reactions.

코로나19병리치료법_보도 자료.docx

PIIS2589004222005442 (4).pdf

Dapsone for Alzheimer Disease Exacerbation as a Preventive Therapeutic OptionResearchers sought to assess the clinical prevalence of Alzheimer disease in patients with leprosy, also known as Hansen’s disease, and inflammasome activity.

The listed, delisted, and sustainability of therapeutic medicines for dementia patients: the study is specific to South Korea - Naunyn-Schmiedeberg's Archives of Pharmacology

Lee-2022-Naunyn-Schmiedeberg's_Archives_of_Pharmacology.pdf

202202 치매약의 안전성에 대한 논문 발표

코비드-19 치료법을 제시하다

Benefits of Using Dapsone in Patients Hospitalized with COVID-19

vaccines-10-00195-v2 (2).pdf

20220125 중증 호흡부전 코비드-19 치료제로서 답손의 임상치료 결과 논문 발표

Specific Treatment Exists for SARS-CoV-2 ARDS

20210618 SARS-CoV-2 급성호흡부전의 치료제는 존재한다

코비드-19 치료 이론을 제시하다.

ijms-21-05953-v2.pdf

4,4′-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor

20201104 Old drug, new therapy - COVID-19 임상 3상에 사용된 오래된 약 답손

http://www.yes24.com/Product/Goods/103415894

http://www.yes24.com/Product/Goods/103012786

2021.6.11 보도 자료 ; 코비드-19 호흡부전과 알츠하이머병 치료제 논문 발표 세 건

Karger 515926.pdf

www.karger.com/Article/FullText/515926

20210611 Science Research Center 코비드알츠하이머병연구 보도자료

2021.06.19 알츠하이머병 치료 중 발생하는 뇌졸증 치료와 치매약의 위험성 발표 https://www.karger.com/Article/FullText/516074

Karger 516074.pdf

The Neuroinflammasome in Alzheimer’s Disease and Cerebral Stroke

20210622 알츠하이머병 환자를 치료할 때 주의해야 할 것에 대한 발표 논문(2)

2020-02-03 경도인지장애 치료법 발표 https://www.karger.com/Article/FullText/504880

504880.pdf

Recovery of Dementia Syndrome following Treatment of Brain Inflammation

20200203 뇌세포의 염증 치료를 통한 치매증후군의 예방 및 치료 발표

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